IMPACT OF BARIATRIC SURGERY ON CONCEPTION AND PREGNANCY OUTCOMES IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME (PCOS): A PROSPECTIVE STUDY OF ONE YEAR

Abstract

Introduction: In obese patients with PCOS, even a small weight loss of up to 5% of the initial body weight can cause spontaneous ovulation, the restoration of regular menstrual cycles, and conception. The aim of this prospective study was to determine the outcomes of Bariatric Surgery in terms of Conception and Pregnancy in patients with Polycystic Ovary Syndrome (PCOS).

Material & Methods: This prospective study was conducted at International metabolic and bariatric center, Afridi medical complex, Peshawar on patients who underwent bariatric surgery from February 2021 till February 2022 with one year follow up period. A total of 518 premenopausal women who attended the facility during the study period were included in the study. Patients who met the Rotterdam criteria for PCOS and were between the ages of 18 and 45 were recruited. It was mandatory for the participants to have had bariatric surgery, such as a sleeve gastrectomy or gastric bypass, within the previous year. Baseline demographic and clinical data was noted while conception rate and pregnancy outcomes were assessed in follow up. Data was analyzed using SPSS version 26.

Results: A total of 62 patients (12%) had Polycystic Ovary Syndrome (PCOS) diagnosis. Following one year after the bariatric surgery, forty of the participants became pregnant accounting for conception rate of 65% of the total individuals. The majority of pregnancies resulted in live births, accounting for 38 (95%) of cases. Miscarriages occurred in only 1(3%) of pregnancies. Additionally, 5(12%) of newborns were underweight while 2(5%) were overweight at birth.

Conclusion: The findings of our study concluded that bariatric surgery is a safe and effective therapeutic alternative for enhancing reproductive function, conception rate and better pregnancy outcomes in females suffering from polycystic ovary syndrome.